2022 Quality Summit ePosters (Non-CE) - CathPCI Registry-17. Effect and Safety of Universal High-Dose Hydration Protocol on Post-PCI Serum Creatinine: A 4-year Cumulative Experience [Third Place ePoster Winner]

17. Effect and Safety of Universal High-Dose Hydration Protocol on Post-PCI Serum Creatinine: A 4-year Cumulative Experience [Third Place ePoster Winner]

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Pdf Summary

The document discusses the implementation of a new high-dose hydration protocol (HDHP) for all patients undergoing percutaneous coronary intervention (PCI) to potentially reduce the incidence of acute kidney injury (AKI) and improve patient outcomes. AKI is a significant complication of PCI, and peri-procedural hydration is commonly used to mitigate the risk. However, the optimal dosage of hydration remains uncertain. <br /><br />A previous pilot study conducted from April 2018 to January 2020 found that patients who received universal HDHP after PCI had a significant decrease in post-procedural serum creatinine levels compared to the control group. Encouraged by these findings, the protocol was continued prospectively for an additional 28 months, including 155 more patients from February 2020 to May 2022. The new data set reaffirmed the previous results, demonstrating a statistically significant reduction in serum creatinine levels in the HDHP group compared to the control group. By including more patients and extending the study period, the authors were able to validate and strengthen their initial findings.<br /><br />The document also includes additional background information on AKI and references to relevant studies. It concludes by noting that the study's findings provide evidence for the effectiveness and safety of the universal HDHP for all PCI patients.

Keywords

high-dose hydration protocol

percutaneous coronary intervention

acute kidney injury

patient outcomes

peri-procedural hydration

dosage of hydration

serum creatinine levels

control group

prospective study

universal HDHP